Skip to main content

Acrylamide Formation in Different Foods and Potential Strategies for Reduction

  • Conference paper
Chemistry and Safety of Acrylamide in Food

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 561))

Abstract

This paper summarizes the progress made to date on acrylamide research pertaining to analytical methods, mechanisms of formation, and mitigation research in the major food categories. Initial difficulties with the establishment of reliable analytical methods have today in most cases been overcome, but challenges still remain in terms of the needs to develop simple and rapid test methods. Several researchers have identified that the main pathway of formation of acrylamide in foods is linked to the Maillard reaction and in particular the amino acid asparagine. Decarboxylation of the resulting Schiff base is a key step, and the reaction product may either furnish acrylamide directly or via 3-aminopropionamide. An alternative proposal is that the corresponding decarboxylated Amadori compound may release acrylamide by a beta-elimination reaction. Many experimental trials have been conducted in different foods, and a number of possible measures identified to relatively lower the amounts of acrylamide in food. The validity of laboratory trials must, however, be assessed under actual food processing conditions. Some progress in relatively lowering acrylamide in certain food categories has been achieved, but can at this stage be considered marginal. However, any options that are chosen to reduce acrylamide must be technologically feasible and also not negatively impact the quality and safety of the final product.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Amrein, T.M., Bachmann, S., Noti, A., Biedermann, M., Barbosa, M.F., Biedermann-Brem, S., Grob, K., Keiser, A., Realini, P., Escher, F., and Amado, R., 2003, Potential of acrylamide formation, sugars, and free asparagine in potatoes: a comparison of cultivars and farming systems, J. Agric. Food Chem. 51: 5556–5560.

    Article  CAS  Google Scholar 

  • Amrein, T. M., Schoenbaechler, B., Escher, F., and Amado, R., 2004, Acrylamide in gingerbread: critical factors for formation and possible ways for reduction, J. Agric. Food Chem. 52: 4282–4288.

    Article  CAS  Google Scholar 

  • Andrzejewski, D., Roach, J.A.G., Gay, M.L., and Musser, S.M., 2004, Analysis of coffee for the presence of acrylamide by LC-MS/MS, J. Agric. Food Chem. 52: 1996–2002.

    Article  CAS  Google Scholar 

  • Becalski, A, Lau, B. P-Y, Lewis, D and Seaman, S., 2003, Acrylamide in foods: Occurrence, sources and modelling, J. Agric. Food Chem. 51: 802–808.

    Article  CAS  Google Scholar 

  • Biedermann, M. Biedermann-Brem, S. Noti, A. and Grob, K., 2002a, Methods for determining the potential of acrylamide formation and its elimination in raw materials for food preparation, such as potatoes, Mitt. Lebensm. Hyg. 93: 653–667.

    CAS  Google Scholar 

  • Biedermann, M., Noti, A., Biedermann-Brem, S., Mozzetti, V. and Grob, K., 2002b, Experiments on acrylamide formation and possibilities to decrease the potential of acrylamide formation in potatoes, Mitt. Lebensm. Hyg. 93: 668–687.

    CAS  Google Scholar 

  • Blank, I., Robert, F., Vuataz, G., Pollien, P., Saucy, F., and Stadler, R. H., 2004, A new insight into the formation of acrylamide via the early Maillard reaction. Abstracts of Papers, 227th ACS National Meeting, Anaheim, CA, United States, March 28–April 1.

    Google Scholar 

  • Delatour, T., Perisset, A., Goldmann, T., Riediker, S., and Stadler, R.H. Improved sample preparation to determine acrylamide in difficult matrices such as chocolate powder, cocoa, coffee, and surrogates by liquid chromatography tandem mass spectroscopy. J. Agric. Food Chem. 52: 4625–4631.

    Google Scholar 

  • Franke, K., Kreyenmeier, F., and Reimerdes, E. H., 2003, Acrylamide-taking a comprehensive look at the events surrounding its formation is critical! Lebensmitteltechnik; 35(3): 60–62.

    Google Scholar 

  • Friedman, M., 2003, Chemistry, biochemistry, and safety of acrylamide, J. Agric. Food Chem. 51:4504–4526.

    Article  CAS  Google Scholar 

  • Gama-Baumgartner, F., Grob, K., and Biedermann, M., 2004, Citric acid to reduce acrylamide formation in French fries and roasted potatoes? Mitt. Lebensm. Hyg. 95(1): 110–117.

    CAS  Google Scholar 

  • Gertz, C., Klostermann, S., and Kochhar, S.P., 2003, Deep frying: the role of water from food being fried and acrylamide formation, Lipides, 2003, 10(4): 297–303.

    CAS  Google Scholar 

  • Gertz, C., and Klostermann, S., 2002, Analysis of acrylamide and mechanisms of its formation in deep-fried products, Eur. J. Lipid Sci. Technol. 104: 762–771.

    Article  CAS  Google Scholar 

  • Grob, K., Biedermann, M., Biedermann-Brem, S., Noti, A., Imhof, D., Amrein, T., Pfefferle, A., and Bazzocco, D., 2003, French fries with less than 100 μg/kg acrylamide. A collaboration between cooks and analysts. Eur. Food Res. Technol. 217: 185–194.

    Article  CAS  Google Scholar 

  • Haase, N.U., Matthaeus, B., and Vosmann, K., 2003, Acrylamide formation in foodstuffs — minimizing strategies for potato crisps. Deutsche Lebensm. Rund. 99: 87–90.

    CAS  Google Scholar 

  • Joint European Commission Workshop “Analytical methods for acrylamide determination in food”, Joint European Commission (DG Sanco & DG JRC)/Swedish National Food Administration, 28–29th April, 2003.

    Google Scholar 

  • Jung, M.Y., Choi, D.S., and Ju, J.W., 2003, A novel technique for limitation of acrylamide formation in fried and baked corn chips and french fries, J. Food. Sci. 68: 1287–1290.

    CAS  Google Scholar 

  • Lingnert, H., Grivas, S., Jagerstad, M., Skog, K., Tornqvist, M., and Aman, P., 2002, Acrylamide in food: mechanisms of formation and influencing factors during heating of food, Scand. J. Nutr. 46(4): 159–172.

    Article  Google Scholar 

  • Mottram, D S, Wedzicha, B I, and Dodson, A T. 2002, Acrylamide is formed in the Maillard reaction, Nature 419: 448.

    Article  CAS  Google Scholar 

  • Noti, A., Biedermann-Brem, S., Biedermann, M., Grob, K., Albisser, P., and Realini, P., 2003, Storage of potatoes at low temperature should be avoided to prevent increased acrylamide during frying or roasting, Mitt. Lebensm. Hyg. 94:167–180.

    CAS  Google Scholar 

  • Roach, J.A.G.; Andrzejewski, D.; Gay, M.L.; Nortrup, D.; Musser, S.M. 2003, Rugged LCMS/MS survey analysis for acrylamide in foods. J. Agric. Food Chem., 51: 7547–7554.

    Article  CAS  Google Scholar 

  • Riediker, S., and Stadler, R.H., 2003, Analysis of Acrylamide in Food Using Isotope-Dilution Liquid Chromatography Coupled with Electrospray Ionization Tandem Mass Spectrometry, J. Chrom. A. 1020: 121–130.

    Article  CAS  Google Scholar 

  • Sanders, R. A., Zyzak, D. V., Stojanovic, M., Tallmadge, D. H., Eberhart, B. L., and Ewald, D. K., 2002, An LC/MS acrylamide method and it’s use in investigating the role of Asparagine. Presentation at the Annual AOAC International Meeting, Los Angeles, CA, September 22–26.

    Google Scholar 

  • Springer, M., Fischer, T., Lehrack, A., and Freund, W., 2003, Acrylamide formation in baked products, Getreide, Mehl und Brot, 57(5): 274–278.

    CAS  Google Scholar 

  • Stadler, R. H., Blank, I., Varga, N., Robert, F., Hau, J., Guy, P. A., Robert, M-C. and Riediker, S. Acrylamide from Maillard reaction products. Nature 419, 449 (2002).

    Article  CAS  Google Scholar 

  • Stadler, R.H., Verzegnassi, L., Varga, N., Grigirov, M., Studer, A., Riediker, S., and Schilter, B., 2003, Formation of vinylogous compounds in model Maillard reaction systems. Chem. Res. Tox. 16: 1242–1250.

    Article  CAS  Google Scholar 

  • Surdyk, N., Rosen, J., Andersson, R., and Aaman, P., 2004, Effects of Asparagine, Fructose, and Baking Conditions on Acrylamide Content in Yeast-Leavened Wheat Bread, J. Agric. Food Chem. 52(7): 2047–2051.

    Article  CAS  Google Scholar 

  • Tareke, E.P., Rydberg, P., Karlsson, S., Erikson, M., and Törnqvist, M., 2002, Analysis of acrylamide, a carcinogen formed in heated foodstuffs, J. Agric. Food Chem. 50: 4998–5006.

    Article  CAS  Google Scholar 

  • Taeymans, D., Ashby, P., Blank, I., Gondé, P., van Eijck, P., Lalljie, S., Lingnert, H., Lindblom, M., Matissek, R., Müller, D., O’Brien, J., Thompson, S., Studer, A., Silvani, D., Tallmadge, D., Whitmore, T., Wood, J., and Stadler, R.H., 2004, A review of acrylamide: an industry perspective on research, analysis, formation and control, Crit. Rev. Food Sci & Nutr., in press.

    Google Scholar 

  • Vattem, D.A., and Shetty, K., 2003, Acrylamide in food: a model for mechanism of formation and its reduction, Inn. Food Sci. and Emerging Technol. 4: 331–338.

    Article  CAS  Google Scholar 

  • Wenzl, T., de la Calle, B., and Anklam, E., 2003, Analytical methods for the determination of acrylamide in food products: a review, Food Addit. Contam. 20: 885–902.

    Article  CAS  Google Scholar 

  • Yasuhara, A., Tanaka, Y., Hengel, M., and Shibamoto, T., 2003, Gas chromatographic investigation of acrylamide formation in browning model systems, J. Agric. Food Chem. 51: 3999–4003.

    Article  CAS  Google Scholar 

  • Yaylayan, V.A., Wnorowski, A., and Locas, C.P., 2003, Why asparagine needs carbohydrates to generate acrylamide, J. Agric. Food Chem. 51: 1753–1757.

    Article  CAS  Google Scholar 

  • Zyzak, D., Sanders, R.A., Stojanovic, M., Tallmadge, D., Eberhart, B.L., Ewald, D.K., Gruber, D.C., Morsch, T.R., Strothers, M.A., Rizzi, G.P., Villagran, M.D., 2003, Acrylamide formation mechanism in heated foods, J. Agric. Food Chem. 51: 4782–4787.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2005 Springer Science+Business Media, Inc.

About this paper

Cite this paper

Stadler, R.H. (2005). Acrylamide Formation in Different Foods and Potential Strategies for Reduction. In: Friedman, M., Mottram, D. (eds) Chemistry and Safety of Acrylamide in Food. Advances in Experimental Medicine and Biology, vol 561. Springer, Boston, MA. https://doi.org/10.1007/0-387-24980-X_13

Download citation

Publish with us

Policies and ethics